The Rise of Biostimulators: Why Filipinos Are Embracing Regenerative Treatments
And why you should, too.
In the ever-evolving world of skincare, trends come and go, but some innovations leave a lasting impact. One such breakthrough is the rise of biostimulators—treatments designed to enhance the skin’s natural ability to repair, rejuvenate, and regenerate. While Filipinos have long been drawn to K-beauty and aesthetic treatments, the shift towards regenerative skincare marks a new era of self-care.
Among these biostimulator treatments are Rejuran, Exosome Therapy, and ASCE+ (Advanced Skincare Complex from ExoCoBio), all of which are gaining popularity for their ability to deliver long-term, natural-looking results.
What Are Biostimulators?
Unlike traditional dermal fillers that provide immediate volume, biostimulators work beneath the surface, stimulating collagen and elastin production over time. This makes them an appealing choice for those seeking gradual yet lasting improvements in skin texture, firmness, and overall health. Globally, popular biostimulators include Poly-L-lactic Acid (PLLA) and Calcium Hydroxylapatite (CaHA), but in the Philippines, three treatments—Rejuran, Exosome Therapy, and ASCE+—are garnering attention.
Rejuran: The Power of Polynucleotides (PN)
Rejuran, often referred to as the “skin healer,” is a biostimulator derived from polynucleotides (PN), a DNA component sourced from salmon. This innovative treatment has been celebrated for its ability to repair damaged skin, reduce signs of aging, and improve overall skin quality.Rejuran is administered through microinjections that deliver polynucleotides into the skin, stimulating fibroblast activity and enhancing collagen synthesis. The result? Improved elasticity, hydration, and a more youthful complexion. Unlike traditional fillers that merely plump the skin, Rejuran works at the cellular level to encourage long-term rejuvenation.
Rejuran comes in different formulations tailored for specific concerns:
- Rejuran Healer (H): A go-to solution for overall skin rejuvenation, targeting wrinkles, dullness, enlarged pores, and sagging.
- Rejuran I: Designed for the delicate eye area, helping reduce fine lines and improve skin resilience.
- Rejuran S: A specialized formula for acne scars, promoting skin regeneration and texture refinement.
The treatment is particularly popular among Filipinos dealing with sun damage, acne scars, and early signs of aging—common concerns given the country’s humid climate and year-round sun exposure.
Exosome Therapy: The Future of Skin Regeneration
Another revolutionary biostimulator is Exosome Therapy. This treatment harnesses the power of exosomes—tiny extracellular vesicles packed with growth factors, peptides, and RNA that facilitate intercellular communication and tissue repair. While stem cell therapies have been making waves in the medical field, exosomes take this concept further by amplifying the body’s natural regenerative capabilities without the ethical concerns associated with stem cells.
Exosomes act as messengers, delivering potent regenerative signals to skin cells. When applied through a topical solution or combined with microneedling, exosomes enhance cell turnover, boost collagen production, and repair damaged tissue. The result is visibly healthier, more resilient skin with improved hydration and elasticity.
It’s particularly beneficial for individuals looking to combat hyperpigmentation and melasma, skin laxity and fine lines, and post-procedure healing.
ASCE+: A Biostimulator Treatment Powered by Exosomes
ASCE+, or Advanced Skincare Complex from ExoCoBio, is another biostimulator making waves in regenerative skincare. Utilizing exosome technology, ASCE+ is rich in growth factors, anti-inflammatory cytokines, and peptides that promote skin healing and rejuvenation. By enhancing collagen production and reducing inflammation, ASCE+ improves skin texture, tone, and elasticity, making it an excellent option for those looking to achieve a youthful, radiant complexion.
The Hype Behind Biostimulators
These days, more and more Filipinos are embracing regenerative skincare, seeking treatments that not only correct but also prevent premature aging. Biostimulators fit this approach by providing long-term skin benefits rather than quick fixes.
The influence of K-beauty also plays a significant role, as treatments like Rejuran, Exosome Therapy, and ASCE+, widely used in Korean dermatology, appeal to beauty-conscious Filipinos.
Additionally, the preference for natural-looking results is driving the demand for biostimulators. Unlike traditional aesthetic procedures that may create an overly “done” appearance, these treatments enhance natural features gradually, resulting in a fresh, youthful glow.
What to Expect
While Rejuran, Exosome Therapy, and ASCE+ offer promising results, they require patience and consistency. Here’s what to keep in mind when considering these treatments:
- Multiple sessions may be needed – Results are not immediate, as collagen and elastin production take time. Most patients require at least 3 sessions spaced a around four weeks apart.
- Minimal downtime – Mild redness and swelling may occur post-treatment, but these side effects typically subside within a few days.
- Long-lasting effects – Unlike traditional fillers that last 6 to 12 months, biostimulators continue to improve skin quality over several months, with results lasting up to two years.
For sure, the rise of biostimulators signifies a new era in skincare—one that prioritizes long-term regeneration over quick fixes. As more Filipinos embrace these treatments, the focus shifts from superficial enhancements to true skin health. As always, consulting a board-certified dermatologist is essential to ensure the right treatment plan tailored to your skin’s unique needs.
At Bella Pelle Skin Solutions, Rejuran starts at P15,000 for Rejuran I (Eye treatment) and Rejuran S (Scar), and starts at P25,000 for Rejuran H (Healer). Exosome Therapy starts at P25,000, while ASCE+ starts at P20,000.
To know more or to book an appointment, call or text (63) 999-887-1933. You can also book a face-to-face or virtual dermatological consultation with Dr. Maximin Navarro, our resident dermatologist and a Philippine Dermatological Society (PDS) fellow, here. For a full list of facial services and other treatments, click here.
Bella Pelle Skin Solutions is located 2/F L Building, #142 Katipunan, Brgy. Saint Ignatius, Quezon City. The center is open Monday to Friday, from 9 a.m. to 6 p.m.
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